Uganda’s healthy climate makes it possible to get on with life with a minimum of fuss. You have to take precaution against malaria by taking anti-malarial two weeks before arrival. All kinds of anti-malaria is available in drug shops and there are doctors who have been in the country for many years who will treat malaria successfully.
Nearly all-African doctors are good at treating most tropical diseases. Some malaria strains now are resistant to treatments like malaria-quine or quinine, so its is better to always take precautions such as using mosquito repellents, creams or sleeping under treated bed-nets. You could also put on long sleeved shirts, socks and occasionally use sprays in your room. You are meanwhile advised to drink bottled mineral water, although tap water in most places can be drunk without problems.
Some visitors to Uganda find a problem coping with fresh vegetables or fruit salads served in hotels, but the problem is usually not that of parasite infection but a change in climate for visitors.
You should be able to drink most fresh juices and salads served in most decent hotels. Otherwise washing vegetables or fruits in a tincture of vinegar or salt is recommended. You might want to swim in most of the lakes or rivers, but a precaution should be taken against Schistomiasis (bilharzias).
There was an outbreak of Yellow Fever in northern Uganda in December 2010. You should ensure that your vaccination is up to date before arriving in Uganda. You should also take a valid Yellow Fever vaccination certificate with you, as you may be asked to produce this when traveling onward from Uganda to other countries.
Very urgently recommended are vaccination against hepatitis A and typhoid fever. From October to May is recommended vaccination against meningococcal meningitis. In case of a longer stay, is recommended vaccination against hepatitis B and against cholera. For those travelers who will not stay mainly in the towns, is recommended vaccination against rabies. People over 30 years should be re-vaccinated against diphtheria and polio. Before travelling you should check, if you are vaccinated against tetanus and measles.